ANALYTICAL METHODS FOR THE QUANTITATION OF AMLODIPINE BESYLATE AND ATORVASTATIN CALCIUM IN PHARMACEUTICAL DOSAGE FORM AND BIOLOGICAL FLUIDS
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چکیده
منابع مشابه
Validated Chromatographic Methods for Simultaneous Determination of Amlodipine Besylate and Perindopril Arginine in Binary Mixtures and in Pharmaceutical Dosage Form
The developed RP-HPLC depends on quantitative chromatographic separation of the studied drugs on a C18 column using phosphate Buffer:acetonitrile (60:40, v/v), pH=4.6 as a mobile phase delivered at constant flow rate of 1 mL.min-1 with UV detection at 210 nm. Calibration curves for Amlodipine besylate and Perindopril Arginine were constructed over the concentration range of 1-50 μg.mL-1 for bot...
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Copyright: © 2014 Hafez HM, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Development of a Stability-Indicating HPLC Method for Simultaneous Determination of Amlodipine Besylate and Atorvastatin Calci...
متن کاملSimultaneous Spectrophotometric Estimation of Atorvastatin Calcium and Amlodipine Besylate in Tablet Dosage Forms
A simple and economical dual wavelength spectrophotometric method has been developed for the simultaneous estimation of atorvastatin calcium and amlodipine besylate in their combined dosage forms. The method was based on property of additivity of absorbances. The two wavelengths on amlodipine besylate curve were found out where it showed same absorbance, which were 257.4 and 360.0 nm. At 360.0 ...
متن کاملSimultaneous Estimation of Telmisartan and Amlodipine Besylate in Pharmaceutical Dosage Form by Rp – Hplc
The chromatographic analysis was performed on ODS symmetry C18 column (150 × 4.6 mm, 5 μ particle size) with mobile phase consisting of acetonitrile and phosphate buffer (pH 4.0) in the ratio of 60:40 v/v, at a flow rate of 1.2 mL/min and eluents monitored at 237 nm. The method was validated for linearity, accuracy, precision, robustness and application for assay as per International Conference...
متن کاملApplication of smart spectrophotometric methods and artificial neural network for the simultaneous quantitation of olmesartan medoxamil, amlodipine besylate and hydrochlorothiazide in their combined pharmaceutical dosage form
BACKGROUND New, simple and specific spectrophotometric methods and artificial neural network (ANN) were developed and validated in accordance with ICH guidelines for the simultaneous estimation of Olmesartan (OLM), Amlodipine (AML), and Hydrochlorothiazide (HCT) in commercial tablets. RESULTS For spectrophotometric methods: First, Amlodipine (AML) was determined by direct spectrophotometry at...
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ژورنال
عنوان ژورنال: International Journal of Applied Pharmaceutics
سال: 2019
ISSN: 0975-7058
DOI: 10.22159/ijap.2019v11i3.32566